Table 4 Temporal and spatial expression of VLDLR and ApoER2 within developing embryonic mouse brain [22, 23].
From: Similarities and differences in structure, expression, and functions of VLDLR and ApoER2
Developmental day | E12 | E12.5-13.5 | E15-E15.5 | E16.5-E17 | E18 | P0-P6 |
|---|---|---|---|---|---|---|
VLDLR | Low expression in preplate | Intermediate zone and cortical plate | Developing hippocampus; palaeocortex; neocortical plate; Cajal-Retzius cells; subplate; deep layers of cerebellum | All areas as E15 | All areas as E15, plus: Stronger expression in Cajal-Retzius cells; Purkinje cells | Subplate and pyramidal cells of layers III and V; Cajal-Retzius cells; Purkinje cells |
ApoER2 | Low expression in preplate | Inner and middle locations of cortex | Medial cortical fields; olfactory bulb; ubiquitously in cerebellum | Outermost cortex; deeper cerebellar layers | Developing hippocampus; palaeocortex; neocortical plate, subplate | Subplate and pyramidal cells of layers III and V |