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Table 4 Temporal and spatial expression of VLDLR and ApoER2 within developing embryonic mouse brain [22, 23].

From: Similarities and differences in structure, expression, and functions of VLDLR and ApoER2

Developmental day E12 E12.5-13.5 E15-E15.5 E16.5-E17 E18 P0-P6
VLDLR Low expression in preplate Intermediate zone and cortical plate Developing hippocampus; palaeocortex; neocortical plate; Cajal-Retzius cells; subplate; deep layers of cerebellum All areas as E15 All areas as E15, plus: Stronger expression in Cajal-Retzius cells; Purkinje cells Subplate and pyramidal cells of layers III and V; Cajal-Retzius cells; Purkinje cells
ApoER2 Low expression in preplate Inner and middle locations of cortex Medial cortical fields; olfactory bulb; ubiquitously in cerebellum Outermost cortex; deeper cerebellar layers Developing hippocampus; palaeocortex; neocortical plate, subplate Subplate and pyramidal cells of layers III and V