Figure 2From: PGC-1alpha downstream transcription factors NRF-1 and TFAM are genetic modifiers of Huntington diseaseATP concentration in HD patients. Box plot shows medians, quartiles and extreme values. The mean ATP levels of HD patients with the TT genotype (600.6 ± 48.7 ng, n = 9) and those carrying at least one rare NRF-1 rs7781972 allele (TA and AA, 487.1 ± 179 ng, n = 8; 436.7 ± 135.1 ng, n = 4) were significantly different (p = 0.03 two-sample t test).Back to article page