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Table 5 Analysis of RA-SNP's Association with AD in Stage 2, Age-Matched to Stage 1.

From: Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease

Uncorrected Logistic Regression Regression Corrected for Age, Sex and APOE
CHR SNP OR L95 U95 P OR L95 U95 P
21 rs2837960 1.218 0.922 1.609 0.165 1.225 0.903 1.664 0.192
18 rs2002842 1.002 0.802 1.253 0.983 1.013 0.794 1.292 0.920
9 rs3761847 0.897 0.723 1.113 0.324 0.878 0.694 1.110 0.278
  1. The three RA-associated SNPs suggesting association with AD were tested further for their association with AD risk by using logistic in a series of 912 non-AD and 186 AD individuals whose ages more closely resembled those of Stage 1 individuals. Although significant associations were not observed between these SNPs and AD, the results for each SNP were not significantly different from those obtained in Stage 1.