Figure 1From: Anchored FRET sensors detect local caspase activation prior to neuronal degenerationSchematic illustration of local or global caspase activation. (A) Microtubule-anchored FRET sensors for spatiotemporal detection of caspase activation in live cells. (B) Different scenarios (1-4) after apoptotic stimuli of differentiated neuronal cells expressing a microtubule-anchored FRET sensor for a specific caspase (in this study: caspase-3, -6, or -9).Back to article page