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Figure 3 | Molecular Neurodegeneration

Figure 3

From: Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk

Figure 3

Rs3846662 is not associated with percent HMGCRΔ13 in human brain. However, we are underpowered to observe a significant difference (p ≤ 0.05) in percent HMGCRΔ13 between rs3846662 genotypes given the overall high level of exon 13 inclusion in brain cDNA and the possibility that rs3846662 may affect HMGCR exon 13 in a cell-type dependent manner.

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Molecular Neurodegeneration

ISSN: 1750-1326