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Table 1 Classification of human hippocampal brain sections

From: Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold

Case

Case Code

Age

Gender

Pmi [h]

CDR

MMSE

BraakNFT

BraakNP

Diagnosis

Control 1

99-111

75

M

6

0

29

1

1

C

Control 2

00-96

91

W

10

0

28

2

1

C

Control 3

02-55

82

M

4.5

0

28

2

1

C

Control 4

99-121

82

M

7

0.5

26

1

1

C

MCI 1

00-37

90

W

4

0.5

28

2

1

MCI

MCI 2

00-33

77

W

8

0.5

27

2

2

MCI

MCI 3

00-61

87

W

8

0.5

27

2

1

MCI

MCI 4

99-105

85

M

4.5

0.5

20

3

1

MCI

AD 1

99-68

88

M

8

2

13

3

3

AD

AD 2

00-58

85

M

6

2

20

4

2

AD

AD 3

99-96

90

M

2

2

10

6

3

AD

AD 4

98-15

85

W

11

3

11

6

4

AD

AD 5

99-67

95

W

3

3

0

5

4

AD

AD 6

99-98

102

W

11

3

0

6

4

AD

  1. Hippocampal sections of human brains were used and classified as "Control", "MCI" and "AD" (m: man; w: woman; pmi: postmortem interval; CDR: Clinical Dementia Rating score; MMSE: Mini-Mental State Examination score; BraakNFT; neurofibrillary tangles Braak score; BraakNP: neuritic plaques Braak score; C: Control; MCI: mild cognitive impairment; AD: severe Alzheimer's disease).
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Molecular Neurodegeneration

ISSN: 1750-1326