Table 1 Enriched KEGG pathways among the 115 changed transcripts
From: Decreased expression of B cell related genes in leukocytes of women with Parkinson's disease
KEGG pathway | Genes in pathway | Enrichment |
|---|---|---|
B cell receptor signaling pathway | BLNK, CD19, CD22, CD72, CD79A, CD79B, CR2, RASGRP3 | O = 8;E = 0.419;R = 19.111;P = 2.21e-8 |
Hematopoietic cell lineage | CD19, CD22, CD8B, CR2, FCER2, IL1R2 | O = 6;E = 0.546;R = 10.995;P = 2.60e-5 |
Type II diabetes mellitus | CACNA1C, CACNA1D, IRS2 | O = 3;E = 0.284;R = 10.560;P = 3.45e-3 |
Calcium signaling pathway | ADCY2, CACNA1C, CACNA1D, GNAL, P2RX5 | O = 5;E = 1.114;R = 4.489;P = 5.78e-3 |
MAPK signaling pathway | CACNA1C, CACNA1D, CACNB4, IL1R2, RASGRF1, RASGRP3 | O = 6;E = 1.779;R = 3.373;P = 9.64e-3 |
ABC transporters - General | ABCA13, ABCB4 | O = 2;E = 0.254;R = 7.868;P = 2.92e-2 |
GnRH signaling pathway | ADCY2, CACNA1C, CACNA1D | O = 3;E = 0.650;R = 4.613;P = 2.93e-2 |
Cell adhesion molecules (CAMs) | CD22, CD40, CD8B | O = 3;E = 0.807;R = 3.716;P = 4.95e-2 |