Molecular Neurodegeneration

Table 2 Correlations between baseline CSF levels of soluble TNF receptors and TACE activity

From: Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease

CSF		TACE	sTNFR1	sTNFR2
Controls	sTNFR1	r_s = 0.491^b	/	r_s = 0.567^c
	sTNFR2	r_s = 0.557^c	r_s = 0.567^c	/
MCI	sTNFR1	r_s = 0.400^c	/	r_s = 0.690^a
	sTNFR2	r_s = 0.311^b	r_s = 0.690^a	/
AD	sTNFR1	r_s = 0.541^c	/	r_s = 0.663^a
	sTNFR2	r_s = 0.508^c	r_s = 0.663^a	/

All data were collected at baseline. Abbreviations: CSF, cerebrospinal fluid; sTNFR, soluble tumor necrosis factor-α receptor; AD: Alzheimer's disease; MCI: mild cognitive impairment; TACE: tumor necrosis factor-a converting enzyme.
^a p < 0.001.
^b p < 0.05.
^c p < 0.01.

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ISSN: 1750-1326

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