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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis

Figure 1

Design of Thy1-mitoDsRed construct used to generate tg mice. A tg construct containing the entire open reading frame of the DsRed2 gene (red) fused in frame with the mitochondrial targeting sequence of the human cytochrome c oxidase subunit VIII gene (orange) was cloned into the Thy1.2 expression cassette at the XhoI site by T4 ligation.

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