Levels of p3-Alc
and Aβ in plasma from clinical populations (Japanese cohort 2). Plasma samples from AD subjects (n = 39) and age-matched nondemented controls (n = 21) were analyzed for levels of p3-Alcα (A) and Aβ40 (B). Total subjects (All, upper panels), female subjects (Female, middle panels) and male subjects (Male, lower panels) are respectively indicated. Statistical analysis was performed using the Mann-Whitney U-test. **, P = 0.0017 (A, upper). ***, P = 0.0006 (A, middle). ***, P < 0.0001 (B, upper). ***, P < 0.0001 (B, middle). *, P = 0.0263 (B, lower).