Figure 4From: Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brainGPX4 is reduced overall but increased relative to cell density in PD SN. A. GPX4 (dark grey) is visibly reduced in SN of PD subjects (n = 12) compared to controls (n = 11). B. Total immunoreactivity of GPX4 is significantly reduced in SN of PD subjects compared to controls (P = 0.0398, Student's t-test). C. GPX4 immunoreactivity is increased relative to cell density (P = 0.0192, Student's t-test). Scale bars: 20 μm.Back to article page