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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

Figure 4

GPX4 is reduced overall but increased relative to cell density in PD SN. A. GPX4 (dark grey) is visibly reduced in SN of PD subjects (n = 12) compared to controls (n = 11). B. Total immunoreactivity of GPX4 is significantly reduced in SN of PD subjects compared to controls (P = 0.0398, Student's t-test). C. GPX4 immunoreactivity is increased relative to cell density (P = 0.0192, Student's t-test). Scale bars: 20 μm.

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