Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

Table 1 Study Subjects.

	Control (n = 11)	PD (n = 12)
Age Range (YR):	76.6-91.7	79.6-92.9
Age at Death (YR):	84.0 ± 1.3	84.2 ± 1.0
Post-Mortem Interval (HR):	17.01 ± 2.7	9.57 ± 4.1
Median (and Range) Braak stage:	0 (0)	5.5 (5-6)
Total SN Cell Density:	21.7 ± 1.9	8.2 ± 1.4^†
Lateral-Ventral SN Cell Density:	27.6 ± 3.3	5.2 ± 1.6^†

† indicates significantly different from controls (P < 0.0001).
HAAS subject information obtained at autopsy. Methods published previously [19].
All decedents were American-born males of Japanese ancestry living in Hawaii. Data are mean ± SEM unless indicated otherwise.

ISSN: 1750-1326