Figure 6
From: Dantrolene is neuroprotective in Huntington's disease transgenic mouse model
Dantrolene feeding inhibits Httexp aggregation in YAC128 striatal cells. The striatal slices from 14 months old control (PBS-fed) and dantrolene-fed WT and YAC128 mice were stained with an anti-Htt monoclonal antibody (dark grey). Nuclei were counter-stained with cresyl violet (blue). Representative images of 3 mice are shown. WT, wild type; YAC, YAC128; Ctrl, control; Dan, dantrolene.