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Table 2 Brain weight and MSN counts of 14 months old WT and YAC128 mice.

From: Dantrolene is neuroprotective in Huntington's disease transgenic mouse model

Group name Number of female mice Brain weight (g) MSN counts (106)
WT-Ctrl 10 0.499 ± 0.01 1.27 ± 0.03
WT-Dan 10 0.495 ± 0.01 1.263 ± 0.03
YAC128-Ctrl 10 0.437 ± 0.01*** 0.997 ± 0.03*
YAC128-Dan 10 0.461 ± 0.01 1.18 ± 0.030#
  1. The brain weight and MSN counts from NeuN staining and stereological analysis are shown as mean ± SE. ***p < 0.001, *p < 0.05 compared to WT-Ctrl and #p < 0.05 compared to YAC128-Ctrl using one-way ANOVA with Tukey's post test.
  2. Pathological analysis of WT and YAC128 mice tissues following dantrolene trial.