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Figure 10 | Molecular Neurodegeneration

Figure 10

From: Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Figure 10

Abnormal MBP staining in brainstem of Hup23 mice. Double immunofluorescence analysis was performed on sagittal brain sections stained with antibodies against p23 (red) and MBP (green) using confocal microscopy. A, Representative lower magnification images of brainstem reveal thinner myelinated bundles in Hup23 brain. B, Higher magnification images of brainstem, staining in hippocampal CA1 region and cerebellum are shown. Unlike the apparent difference observed in brainstem, MBP staining in hippocampus and cerebellum is comparable between Hup23 mice and Ntg littermates.

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