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Table 1 A comparison of p23 overexpression and the onset of phenotype in Hup23 mice

From: Transgenic neuronal overexpression reveals that stringently regulated p23 expression is critical for coordinated movement in mice

Line

Fold overexpression

Symptoms observed by DigiGait analysis

Symptoms visually observed

Age at death

06

1 - 1.5

~P30

~P37

~P60

43

1.4 - 4.9

P20

P22

P33 - 34

61

2.8 - 10.4

N.D.

P14

P17 - 21

74

1.3 - 2.5

P28

P32

P43 - 50

76

1.1 - 2.5

P28

P32

P41 - 48

 

F

1.3 - 1.5

P33

P30

P42 - 44

89

     
 

M

1 - 1.4

P40

P36

Survived

  1. N.D. not determined. F, female; M, male.