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Figure 2 | Molecular Neurodegeneration

Figure 2

From: A novel neuron-enriched protein SDIM1 is down regulated in Alzheimer's brains and attenuates cell death induced by DNAJB4 over-expression in neuro-progenitor cells

Figure 2

Expression pattern of SDIM1 transcript in control and AD human brains. A. Changes in mRNA levels of SDIM1 transcript in control and AD brains were determined by qRT-PCR. The cDNA samples were prepared from pooled mRNA of 4 AD and 5 age-matched control subjects. The value of the control sample was set at 100%. The percentage of the AD sample was calculated by 100x 2-ΔCt, where ΔCt is the cycle number difference between the AD sample and the control sample. The experiments were performed in triplicate. Asterisks indicate a significant difference (p = 0.0014) B. Changes in mRNA levels of SDIM1 transcript in individual control and AD brains were determined by qRT-PCR. The cDNA samples were prepared from mRNA of 9 AD and 10 age-matched control subjects. The qRT-PCR results were calculated against the average result (control mean) of the control samples, set at 100%. Percentage of each sample was calculated by 100 × 2-ΔCt, where ΔCt is the cycle number difference between each sample and the control mean. The experiments were performed in triplicate.

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Molecular Neurodegeneration

ISSN: 1750-1326