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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS

Figure 1

Overexpression of Fus/Caz produces phenotypes and induces growth defects in Drosophila. (A) A wild-type adult wing showing intervein 1-5. (B-F) Adult wings expressing Fus, FusR521G, FusΔ32, Caz, or CazRNAi with UAS-Dicer by the wing-specific MS1096-Gal4. (G) Bar graphs showing adult fly viability assayed at 25°C. (H) Bar graphs showing adult fly viability assayed at 19°C. Overexpressing the indicated constructs by different Gal4 lines induces growth defects or lethality at larval or pupal stages. The # indicates lethality at either the larval or pupal stages.

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Molecular Neurodegeneration

ISSN: 1750-1326