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Figure 5 | Molecular Neurodegeneration

Figure 5

From: Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease

Figure 5

Correlation and linear regression analysis of levels of striatal DARPP-32 mRNA. Using a separate group of mice to those used in our curcumin preclinical trial (n = 23 in total), we correlated levels of DARPP-32 mRNA normalized using HPRT or Atp5b and Eif4a [53]. We found excellent correlation between the results obtained with HPRT and with Atp5b and Eif4a (r2 = 0.862 and slope of 1.08, p < 0.0001).

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