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Figure 4 | Molecular Neurodegeneration

Figure 4

From: The I2020T Leucine-rich repeat kinase 2 transgenic mouse exhibits impaired locomotive ability accompanied by dopaminergic neuron abnormalities

Figure 4

Increased microtubule polymerization in I2020T LRRK2 TG mice. Upper: Brain microtubules of I2020T LRRK2 TG and NTG littermate mice were subjected to in vitro polymerization assay and analyzed by Western blotting. 10 weeks (NTG, n=6; TG, n=6), 32 weeks (NTG, n=4; TG, n=4). Lower: The degree of tubulin polymerization expressed as mean ± SEM and were analyzed by Student’s t test at each time point; *p<0.05.

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Molecular Neurodegeneration

ISSN: 1750-1326