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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Apoptosis-inducing factor downregulation increased neuronal progenitor, but not stem cell, survival in the neonatal hippocampus after cerebral hypoxia-ischemia

Figure 6

Microglia activation after HI. A. Representative Iba-1 (upper panel) and galectin-3 (lower panel) immunostainings in the cortex of both Wt and Hq control brains and 24 h after HI. B. Quantification of Iba-1-positive cells in the cortex did not show any difference between Wt and Hq mice. C. Quantification of galectin-3-positive cells in the cortex 24 h after HI showed fewer pathologically activated microglia in the Hq mice. D. Triple labeling with TUNEL, BrdU and Iba-1 or galectin-3 24 h after HI showing Iba-1- or galectin-3-positive cells engulfing dead cells (TUNEL-positive chromatin fragments).

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Molecular Neurodegeneration

ISSN: 1750-1326