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Figure 1 | Molecular Neurodegeneration

Figure 1

From: LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer’s disease

Figure 1

LRP10 interacts with APP. (A) In vivo interaction of LRP10-HA and GFP-APP695 proteins. Lysates of HEK cells transfected with HA-tagged LRP10 and GFP or GFP-tagged APP were immunoprecipitated with anti-HA and then immunoblotted with anti-HA or anti-GFP antibody to detect LRP10 and GFP, respectively. (B) LRP10-HA interacts with endogenous APP. Lysates of HEK cells transfected with pcDNA3-HA or LRP10-HA were immunoprecipitated with anti-APP antibody and then immunoblotted with anti-HA antibody.

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