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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Bone marrow-derived fibroblast growth factor-2 induces glial cell proliferation in the regenerating peripheral nervous system

Figure 4

Localization of FGF-2 in the regenerating nerve tissue, DRG and lumbar spinal cord. A-H: Optical slices by confocal microscopy of longitudinal sections of sciatic nerve at proximal stump (A and B) or dorsal root ganglia (C and D) and transversal section of lumbar spinal cord (E-H) at the ipsi-lateral (E and F) or contra-lateral region (G and H). All samples were obtained from rats 10 days after treatment with BMMC. Sciatic nerve and DRG sections were double immunolabeled for GFAP/FGF-2 (A and C) and NF-200/FGF-2 (B and D). LSC sections were double immunolabeled for GFAP/FGF-2 and Tuj-1/FGF-2. White arrows indicate yellow areas of colocalisation between glial marker (GFAP) and FGF-2 and neuronal markers (NF-200/Tuj-1) and FGF-2. Scale bar: A-H = 50 βm.

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