No increase in incidence of microhemorrhage in 3A and IAPP oligomer mimic vaccinated mice. A. Representative images of Prussian blue stained sections. Arrowheads point to typical stage 1 microhemorrhages. Scale bar: 25 microns. B. The incidence of microhemorage was counted after staining for hemosiderin. Both the Aß oligomer mimic and Aß fibril vaccinated groups display a much higher incidence of microhemorrhage than the control, 3A or IAPP oligomer vaccinated groups. The mean counts from 3 different sections of each animal is shown +/− the standard error of the mean (n = 8). ***P < 0.001. The 3A oligomer mimics and IAPP vaccinated group.