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Table 2 MicroRNA profiling of alpha-synuclein containing exosomes from primary cortical neuron media

From: Exosomal cell-to-cell transmission of alpha synuclein oligomers

miRNAs

function

remarks

Key citations

27a

activating the expression of P-glycoprotein

present in exosomes

[39][55]

28

inhibitor of thrombopoietin receptor translation

present in exosomes

[39][56]

34a

suppression of cell proliferation through modulation of the E2F signaling pathway

-

[57]

106b

modulation of TGFβ signaling in tumors

present in exosomes

[39][58]

184

Block of NFAT1 protein expression

present in exosomes

[40, 43]

185

Inducion of cell cycle arrest in lung cancer cell lines

present in exosomes

[40, 59]

192

affects cellular proliferation through the p53-miRNA circuit

present in exosomes

[39][60]

199b

Regulation of protein phosphatase 2A inhibitor) in human choriocarcinoma

-

[61]

302b*

regulatory mechanism in tuning stem cell properties

-

[62]

373*

Involvement in tumor migration and invasion

present in exosomes

[39, 46]

422b

-

present in exosomes

[40]

431

-

CNS specific miRNA

[47, 50]

448

-

-

[63]

455

-

-

[51]

487a

Role in angiogenesis and cell aging

-

[52]

491

decreases cell viability by induction of apoptosis

-

[64]

493-3p

-

-

[54]

518*

Predicted to be involved in Huntington’s disease

-

[54, 65]

522

-

present in exosomes

[39]

526a

-

present in exosomes

[39]

526b

-

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