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Table 2 MicroRNA profiling of alpha-synuclein containing exosomes from primary cortical neuron media

From: Exosomal cell-to-cell transmission of alpha synuclein oligomers

miRNAs function remarks Key citations
27a activating the expression of P-glycoprotein present in exosomes [39][55]
28 inhibitor of thrombopoietin receptor translation present in exosomes [39][56]
34a suppression of cell proliferation through modulation of the E2F signaling pathway - [57]
106b modulation of TGFβ signaling in tumors present in exosomes [39][58]
184 Block of NFAT1 protein expression present in exosomes [40, 43]
185 Inducion of cell cycle arrest in lung cancer cell lines present in exosomes [40, 59]
192 affects cellular proliferation through the p53-miRNA circuit present in exosomes [39][60]
199b Regulation of protein phosphatase 2A inhibitor) in human choriocarcinoma - [61]
302b* regulatory mechanism in tuning stem cell properties - [62]
373* Involvement in tumor migration and invasion present in exosomes [39, 46]
422b - present in exosomes [40]
431 - CNS specific miRNA [47, 50]
448 - - [63]
455 - - [51]
487a Role in angiogenesis and cell aging - [52]
491 decreases cell viability by induction of apoptosis - [64]
493-3p - - [54]
518* Predicted to be involved in Huntington’s disease - [54, 65]
522 - present in exosomes [39]
526a - present in exosomes [39]
526b -