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Figure 3 | Molecular Neurodegeneration

Figure 3

From: IκBα deficiency in brain leads to elevated basal neuroinflammation and attenuated response following traumatic brain injury: implications for functional recovery

Figure 3

Elevated neuroinflammation in IκBα cKO mice. (A and C) Representative images of brain sections from 10–15 month-old mice Ctrl and IκBα cKO mice stained against astroglia marker GFAP and microglia marker Iba1. HPC: hippocampus. CTX: cortex. (B and D) Quantification of GFAP- and Iba1- positive cells in HPC and CTX respectively. N = 4/genotype. For each mouse, 3 evenly spaced sections were stained and quantified. ***p < 0.001. Scale bar: 20 μm.

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Molecular Neurodegeneration

ISSN: 1750-1326