Table 3 Gene x Environment Interaction: genes altered by MB/PQ in α-syn-Tg
Accession | Fold change | Gene title | Gene symbol | Functional Group |
|---|---|---|---|---|
NM_145990 | −2.35 | CDK5 regulatory subunit associated protein 2 | Cdk5rap2 | Cell differentiation |
NM_007865 | −1.82 | Delta-like 1 (Drosophila) | Dll1 | |
NM_008380 | −1.80 | Inhibin beta-A | Inhba | |
NM_008711 | −1.68 | Noggin | Nog | |
NM_010894 | −1.33 | Neurogenic differentiation 1 | Neurod1 | |
NM_009170 | −1.33 | Sonic hedgehog | Shh | |
NM_008553 | −1.26 | Achaete-scute complex homolog 1 (Drosophila) | Ascl1 | |
NM_008782 | −1.24 | Paired box gene 5 | Pax5 | |
NM_010275 | −1.25 | Glial cell line derived neurotrophic factor | Gdnf | Growth factors |
NM_009505 | −1.33 | Vascular endothelial growth factor A | Vegfa | |
NM_007553 | −1.28 | Bone morphogenetic protein 2 | Bmp2 | |
NM_007554 | −1.25 | Bone morphogenetic protein 4 | Bmp4 | |
NM_010077 | −1.31 | Dopamine receptor D2 | Drd2 | Synaptic transmission |
NM_013503 | −1.23 | Dopamine receptor D5 | Drd5 | |
NM_013904 | −1.64 | Hairy/enhancer-of-split related with YRPW motif 2 | Hey2 | Transcription |
NM_013905 | −1.61 | Hairy/enhancer-of-split related with YRPW motif-like | Heyl | |
NM_007889 | −1.52 | Dishevelled 3, dsh homolog (Drosophila) | Dvl3 | Cell signaling |
NM_001008533 | −1.30 | Adenosine A1 receptor | Adora1 | |
NM_008744 | −1.39 | Netrin 1 | Ntn1 | Cell motility |
NM_174991 | −1.28 | Brain-specific angiogenesis inhibitor 1 | Bai1 | Cell proliferation |
NM_022312 | −1.27 | Tenascin R | Tnr | Cell adhesion |
NM_013660 | −1.26 | Sema domain, Ig domain, transmembrane domain and short cytoplasmic domain, 4D | Semad4 | Apoptosis |
NM_009685 | −1.38 | Amyloid beta (A4) precursor protein-binding, family B,1 | Apbb1 | Cell cycle |