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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid beta 1-42-induced signal transduction in glial cells

Figure 2

Increased formyl peptide receptors and RAGE expression in microglial cells in a APP/PS1 transgenic mouse model. Coronal brain sections from twelve month old APPswe/PS1dE9 (APP/PS1) or wildtype (WT) mice were stained with anti-ionized calcium binding adaptor molecule-1 (anti-Iba-1) to identify microglial cells (red) and anti-mFPR1 (A), anti-mFPR2 (B) or anti-RAGE (C) (green) antibodies (nuclear counterstaining in blue). The figures show representative results for the cortex and hippocampus from one of three independent experiments (Scale bar = 200 μm for overview and 20 μm for detailed images).

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