Figure 5
From: Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody
MOAB-2 detection of intraneuronal Aβ and extracellular plaques in 5xFAD and 3xTg mouse brain tissues. Immunofluorescent detection of Aβ with MOAB-2 in the subiculum of (A) 1-, 2- and 4-month old 5xFAD mice and (B) 4-, 8- and 24-month old 3xTg mice. (Coronal sections, representative fluorescent images, top = 20x, scale bar 50 μm; bottom = 63x, scale bar 20 μm).