Figure 4
From: In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis
Isoform-dependent differences in apoE levels in the hippocampal ISF. A. ISF samples from the hippocampus of apoE2 KI, apoE3 KI, and apoE4 KI mice were obtained by microdialysis using a constant flow-rate of 1.0 μL/min. ApoE levels were assessed by ELISA and compared by ANOVA followed by Tukey’s post hoc test. * p<0.05, n=3-6 mice per genotype. Data are presented as mean ± SEM. B. 12.5 ng/mL of recombinant apoE2, apoE3, or apoE4 was measured by ELISA and compared by ANOVA (p=0.22).