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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Behavioral characterization of the 6-hydroxidopamine model of Parkinson’s disease and pharmacological rescuing of non-motor deficits

Figure 2

Effect of unilateral dopaminergic degeneration on motor and exploratory behavior. A) Unilateral 6-OHDA lesion caused a significant impairment in motor coordination on the rotarod test for both incomplete and complete lesion groups. B) On the open field arena both 6-OHDA groups display a reduction in total distance travelled. C) Overall reduction in movement initiation in the open field caused by 6-OHDA lesion. Data presented as mean ± SEM. * p < 0.05, *** p < 0.001. For rotarod sham n = 18, incomplete lesion n = 13, complete lesion n = 24. For open field sham n = 18, incomplete lesion n = 13, complete lesion n = 25.

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Molecular Neurodegeneration

ISSN: 1750-1326