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Table 2 Parkinson's disease association analysis of TREM2 variant c.140G>A (rs75932628; p.R47H)

From: TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease

Disorder (n)

Patient, n(%)

Control, n(%)

OR (95% CI)

p-valuea

Control

(1957)

  

8

(0.41)

   

Combined

(1493)

16

(1.07)

8

(0.41)

2.670

(1.13, 6.33)

0.0256

   North American PD

(683)

9

(1.32)

6

(0.45)

3.144

(1.1, 9.03)

0.0333

   Irish PD

(367)

5

(1.36)

2

(0.54)

2.509

(0.47, 13.41)

0.2821

   Polish PD

(443)

2

(0.45)

0

 

NA

NA

 
  1. a Uncorrected p-values are shown.
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Molecular Neurodegeneration

ISSN: 1750-1326