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Figure 1 | Molecular Neurodegeneration

Figure 1

From: The synaptic maintenance problem: membrane recycling, Ca2+homeostasis and late onset degeneration

Figure 1

Synaptic maintenance mechanisms. Several basic maintenance mechanisms operate both pre- and postsynaptically to keep the synape healthy and functional over long periods of time. For each of the indicated processes disruptions have been shown to lead to premature synaptic degeneration independent of any specific neurotoxic insult or neurodegenerative disorder. ER - endoplasmic reticulum; AV - autophagic vacuole; Mito - Mitochondrium; EE - early endosome; EV - endocytic vesicle; SV - synaptic vesicle; Lyso - lysosome.

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