Figure 2
From: Heart fatty acid binding protein and Aβ-associated Alzheimer’s neurodegeneration
(A) Spaghetti plots illustrating atrophy of the entorhinal cortex among all participants classified as low Aβ 1–42 and high HFABP (based on median value of FABP) (top left panel), low Aβ 1–42 and low HFABP (top right panel), high Aβ 1–42 and high FABP (bottom left panel), and high Aβ 1–42 and low FABP (bottom right panel). The red line indicates the mean atrophy rate for the four respective groups (i.e. low Aβ1–42 and high FABP, low Aβ1–42 and low FABP, high Aβ1–42 and high FABP and high Aβ1–42 and low FABP). As illustrated, the slopes of the red lines are significantly different depending on CSF Aβ1–42 status (please see text for further details). (B) Spaghetti plots illustrating atrophy of the entorhinal cortex among all participants classified as high p-tau181p and high HFABP (based on median value of FABP) (top left panel), high p-tau181p and low HFABP (top right panel), low p-tau181p and high FABP (bottom left panel), and low p-tau181p and low FABP (bottom right panel). The red line indicates the mean atrophy rate for the four respective groups (i.e. high p-tau181p and high FABP, high p-tau181p and low FABP, low p-tau181p and high FABP and low p-tau181p and low FABP). As illustrated, the slopes of the red lines are not significantly different depending on CSF p-tau181p status (please see text for further details).