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Table 2 Demographic, clinical, and imaging data for all participants in this study

From: Heart fatty acid binding protein and Aβ-associated Alzheimer’s neurodegeneration

  HC (n = 90) MCI (n = 139) AD (n = 66)
Age, Mean (SE) 76.0 (0.6) 75.1 (0.7) 75.4 (0.9)
Female, % 51 33 41
Education Years, Mean (SE) 15.6 (0.3) 16.1 (0.2) 15.1 (0.4)
MMSE, Mean (SE) 29.1 (0.1) 26.7 (0.1) 23.4 (0.2)
CDR-SB, Mean (SE) 0.03 (0.01) 1.5 (0.07) 4.2 (0.2)
APOE ϵ4 carriers (%) 24 54 71
CSF H-FABP level (ng/ml), Mean (SE) 0.38 (0.03) 0.54 (0.02) 0.58 (0.03)
CSF Aβ1–42 level (pg/ml), Mean (SE) 207.8 (5.6) 157.5 (4.1) 141.5 (2.6)
CSF p-tau181p level (pg/ml), Mean (SE) 24.7 (1.4) 36.8 (1.3) 41.7 (2.6)
Entorhinal Cortex APC, Mean (SE) -0.8 (0.1) -2.4 (0.1) -2.9 (0.2)
AD-vulnerable ROI APC, Mean (SE) -1.1 (0.1) -3.2 (0.2) -3.9 (0.3)
  1. MCI; mild cognitive impairment, HC; cognitively normal older adults, AD; Alzheimer’s disease, MMSE; Mini-mental status exam, CDR-SB; Clinical dementia rating-sum of boxes score, APC; Annualized percent change, SE; Standard error of the mean.