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Table 2 Parameter estimates in the risk-based kinetic models of primary neurodegeneration using the L/R ratio of density of NF at the optic nerve

From: Kinetics of neurodegeneration based on a risk-related biomarker in animal model of glaucoma

 

r 0

β

R 2

P

F-test*

Constant-risk model

0.012

-

0.86

<0.01

-

Variable-risk model

0.0017

0.071

0.98

<0.05

F 1,3  = 22.4, P < 0.05

  1. *F-test compared the two nested models of constant-risk and variable-risk, taking into account the additional parameter β in the latter.