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Figure 3 | Molecular Neurodegeneration

Figure 3

From: Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors

Figure 3

Survival of AHNPC from PS1 M146V KI mice following exposure to EE housing conditions. Histogram shows the survival fraction of BrdU+ AHNPCs in SGL and granular cell layers of PS1 M146V KI following exposure to EE housing conditions. Survival fraction, calculated as a percentage of the BrdU+ cell numbers remaining after 2 weeks over the numbers obtained when animals were sacrificed 24 hr after single dose of 100 mg/kg of BrdU. ANOVA followed by post-hoc LSD test; N = 8, 8, 6 for EE PS1+/+, PS1M146V/+ and PS1M146V/ M146V mice, respectively. ** p < 0.01; #p = 0.051.

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Molecular Neurodegeneration

ISSN: 1750-1326