Table 1 Sample demographics for case-control series
From: ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer’s disease
Series | n (%) | Mean AAD ± SD (Years) | Females (%) | ϵ4+ Subjects (%) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AD | CON | AD | CON | AD | CON | AD | CON | |||||||||
Jacksonville | 1020 | (41.2) | 1453 | (58.8) | 77.7 | (6.46) | 79.5 | (7.86) | 623 | (61.1) | 838 | (57.7) | 653 | (64.0) | 338 | (23.3) |
Rochester | 600 | (19.9) | 2409 | (80.1) | 80 | (7.72) | 78.3 | (5.56) | 363 | (60.5) | 1294 | (53.7) | 328 | (54.7) | 571 | (23.7) |
Poland | 250 | (100) | 0 | (0) | 74.4 | (5.19) | NA | (NA) | 156 | (62.4) | NA | (NA) | 139 | (55.6) | NA | (NA) |
Norway | 345 | (38.5) | 552 | (61.5) | 80.2 | (7.25) | 75.4 | (6.73) | 241 | (69.9) | 330 | (59.8) | 217 | (62.9) | 132 | (23.9) |
NCRAD | 702 | (77.1) | 209 | (22.9) | 75.2 | (6.76) | 78.3 | (8.88) | 455 | (64.8) | 129 | (61.7) | 551 | (78.5) | 34 | (16.3) |
Autopsy* | 1211 | (76.9) | 363 | (23.1) | 81.4 | (8.56) | 75.9 | (8.14) | 695 | (57.4) | 155 | (42.7) | 744 | (61.4) | 98 | (27.0) |
Total | 4128 | (45.3) | 4986 | (54.7) | 78.7 | (7.76) | 78.2 | (6.91) | 2533 | (61.4) | 2746 | (55.1) | 2632 | (63.8) | 1155 | (23.2) |