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Table 1 Effects of antioxidants and calcium chelation on 6-OHDA-disrupted DA mitochondrial transport

From: The Parkinsonian mimetic, 6-OHDA, impairs axonal transport in dopaminergic axons

 

Motile Mitochondria

Control

24.6 ± 1.3%*

6- OHDA

10.3 ± 2.2%

+NAC

25.7 ± 3.3%*

+MnTBAP

28.2 ± 6.5%*

+EGTA

8.34 ± 3.9%

  1. Data indicates mean ± SEM. * indicate p < 0.05 versus 6-OHDA. [NAC] = 2.5 mM, [MnTBAP] = 100 μM, [EGTA] = 2.5 mM.
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