Skip to main content
Figure 6 | Molecular Neurodegeneration

Figure 6

From: Motor and cognitive deficits in aged tau knockout mice in two background strains

Figure 6

Altered movement pattern of tau-/-mice at 12 months of age in Digigait analysis. a) Examples of footprint recorded by the Digigait apparatus. b-h) parameters from Digigait analysis: stride frequency (b), percentage alternate gait where perfectly antiphase stepping is 100% alternate (c), stride length normalized to stance width (d), stride length, stance width, and variability of hindlimb stride of mice in Bl6 background (e), stride length, stance width, and variability of hindlimb stride of mice in Bl6/129sv background (f), paw angle and step angle of mice in Bl6 background (g), and paw angle and step angle of mice in Bl6 background (h). Additional gait analysis can be found in Additional file 5: Figure S5. One-way ANOVA were performed to determine the differences versus age-matched wild type mice for each individual parameter. *p < 0.05, **p < 0.01, ***p < 0.001. n is indicated in the column of each group. Gender distribution is given in Additional file 6: Table S1. Data are means ± SEM.

Back to article page