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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease

Figure 4

The complement-induced inflammation pathway: an important mediator of neuroinflammatory processes from M4 onwards. This functional network was designed using the text-mining software, PredictSearch, based on more stringent criteria than for the above figure: only upregulated DEGs (with a FC > 1.5) found in both the cortex and hippocampus and at consecutive time points (M4/M6; M6/M9 or M4/M6/M9) were considered for analysis. Top right corner: legend for Figures 4, 5, 6, 7.

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