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Table 1 Upregulated genes with their fold change related to inflammation and immune processes in the cortex and hippocampus of 5XFAD mice at M1, M4, M6 and M9

From: Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease

  

Cortex

Hippocampus

Gene

Probe

M1

M4

M6

M9

M1

M4

M6

M9

Clec7a

A51P246653

0.8

12.1

35.0

30.9

1.1

15.9

32.2

32.5

Cst7

A51P137419

1.0

74.7

63.5

140.2

1.3

100.5

118.4

145.8

Itgax

A51P303424

0.7

16.3

13.4

19.6

0.8

16.1

14.8

23.2

Ccl3

A51P140710

1.0

15.8

14.7

15.4

0.6

11.3

7.3

17.3

Ccl6

A51P460954

1.4

12.4

9.4

13.4

1.4

13.7

10.8

9.7

Gfap

A55P2157245

1.1

3.4

6.1

4.4

1.1

2.2

3.0

5.4

Gfap

A52P52303

1.1

5.2

8.4

5.0

1.1

2.8

3.1

4.5

Gfap

A55P2157250

1.2

8.1

8.6

11.8

0.9

4.0

8.0

3.5

Ccl4

A51P509573

0.9

9.0

7.3

9.9

0.9

12.7

10.7

11.3

Ttr

A65P19832

12.2

8.7

2.5

0.7

0.2

1.2

1.0

1.5

Kl

A52P439358

2.9

3.0

1.2

0.5

0.2

1.2

0.6

2.2

  1. Fold changes are indicated in bold when FC > 1.5.