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Table 1 Upregulated genes with their fold change related to inflammation and immune processes in the cortex and hippocampus of 5XFAD mice at M1, M4, M6 and M9

From: Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease

   Cortex Hippocampus
Gene Probe M1 M4 M6 M9 M1 M4 M6 M9
Clec7a A51P246653 0.8 12.1 35.0 30.9 1.1 15.9 32.2 32.5
Cst7 A51P137419 1.0 74.7 63.5 140.2 1.3 100.5 118.4 145.8
Itgax A51P303424 0.7 16.3 13.4 19.6 0.8 16.1 14.8 23.2
Ccl3 A51P140710 1.0 15.8 14.7 15.4 0.6 11.3 7.3 17.3
Ccl6 A51P460954 1.4 12.4 9.4 13.4 1.4 13.7 10.8 9.7
Gfap A55P2157245 1.1 3.4 6.1 4.4 1.1 2.2 3.0 5.4
Gfap A52P52303 1.1 5.2 8.4 5.0 1.1 2.8 3.1 4.5
Gfap A55P2157250 1.2 8.1 8.6 11.8 0.9 4.0 8.0 3.5
Ccl4 A51P509573 0.9 9.0 7.3 9.9 0.9 12.7 10.7 11.3
Ttr A65P19832 12.2 8.7 2.5 0.7 0.2 1.2 1.0 1.5
Kl A52P439358 2.9 3.0 1.2 0.5 0.2 1.2 0.6 2.2
  1. Fold changes are indicated in bold when FC > 1.5.