Figure 1
From: Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene
Associations with age at onset in the overall group of FTD, FTD/MND, and MND probands. Three variants are shown that demonstrate a significant association with age at onset in C9ORF72 expansion carriers (rs7018487:T > G [UBAP1; panel A], rs6052771:A > G [PRNP; panel B], and rs7403881:G > C [MT-Ie; panel C]). In each panel, the mean in the given group is denoted by a solid horizontal line; associations are specified in Table 2 and genotype frequencies in Additional file 1: Table S1.