Figure 2
From: Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene
Variants significantly associated with survival after onset. Six significant associations with survival after onset are presented (rs5848:G > A [GRN; panel A], rs7403881:G > C [MT-Ie; panel B], rs13268953:A > G [ELP3; panel C], the epsilon 4 allele:E4- > E4+ [APOE; panel D], rs12608932:A > C [UNC13A; panel E], and rs1800435G > C [ALAD; panel F]). When three curves are shown (rs5848), zero copies of the minor allele are displayed in black, one copy of the minor allele is displayed in blue, and two copies of the minor allele are displayed in red. If two curves are present (other variants), then the common genotype is shown in black and the rare genotype is shown in blue.