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Table 1 Subject characteristics

From: Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene

Group N Female gender Age Age at onset Pathological diagnosis
Controls 374 172 (46.0%) 61.2 ± 10.2 (35–90) N/A N/A
All repeat expansion carriers 330 149 (45.2%) 59.4 ± 10.0 (35–90) 56.5 ± 9.1 (34–83) 123 (37.3%)
FTD, FTD/MND, and MND probands 265 115 (43.4%) 59.6 ± 10.0 (35–90) 56.8 ± 9.1 (34–83) 112 (42.3%)
FTD probands 74 29 (39.2%) 63.1 ± 12.2 (35–90) 57.7 ± 9.8 (34–79) 45 (60.8%)
FTD/MND probands 71 25 (35.2%) 60.6 ± 8.5 (39–80) 56.2 ± 9.0 (34–74) 51 (71.8%)
MND probands 120 61 (50.8%) 56.9 ± 8.6 (37–83) 56.5 ± 8.7 (36–83) 16 (13.3%)
  1. Continuous variables are summarized with the sample mean ± standard deviation (range). The age provided is age at blood draw in controls, age at onset in clinically diagnosed patients, and age at death in pathologically diagnosed patients. Information was unavailable for age (n = 41) and age at onset (n = 59).