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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-β oligomers and no plaque pathology

Figure 1

APP/Aβ pathology in the hippocampus of Dutch mutant APP and TgCRND8 mutant APP transgenic mice. Aβ and APP species were visualized using the 6E10 antibody. Intracellular APP/Aβ-like immunoreactivity (arrowhead) is evident in DU mice (A and D) while extracellular amyloid plaques (black arrow) are evident in TgCRND8 APP transgenic mice (B and E). No APP/Aβ immunoreactivity is seen in WT mice (C and F). A-C scale = 500 μm; D-F scale = 100 μm.

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Molecular Neurodegeneration

ISSN: 1750-1326