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Figure 3 | Molecular Neurodegeneration

Figure 3

From: Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-β oligomers and no plaque pathology

Figure 3

No significant changes in dendritic spine density in DU mice compared to controls. Representative images of deconvolved WT and DU dendrites in 3D with spine visualization (A & B). When spine density was analyzed, no changes were observed for total, thin, and stubby spines on apical and basal dendrites in DU and WT neurons (C-H). Analysis of mushroom spines revealed a decrease in density however, this did not reach significance (I-K). Data represent group mean ± SEM. Scale bars = 5 μm.

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