Figure 3From: Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-β oligomers and no plaque pathologyNo significant changes in dendritic spine density in DU mice compared to controls. Representative images of deconvolved WT and DU dendrites in 3D with spine visualization (A & B). When spine density was analyzed, no changes were observed for total, thin, and stubby spines on apical and basal dendrites in DU and WT neurons (C-H). Analysis of mushroom spines revealed a decrease in density however, this did not reach significance (I-K). Data represent group mean ± SEM. Scale bars = 5 μm.Back to article page