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Table 1 Apical dendritic, spine and synapse morphology from CA1 pyramidal neurons of DU and WT mice

From: Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-β oligomers and no plaque pathology

 

Genotype

 
 

DU

WT

Apical dendritic length (μm)

1277.65 ± 147.79

1507.37 ± 154.86

Spine density (Spines/μm)

  

Total

2.676 ± 0.164

2.674 ± 0.118

Thin

1.585 ± 0.307

1.548 ± 0.133

Stubby

1.114 ± 0.177

1.007± 0.097

Mushroom

0.199 ± 0.014

0.237± 0.012

Synapse density (μm 3 )

  

Total

2.897 ± 0.304

2.830 ± 0.250

Perforated

0.097 ± 0.013

0.123 ± 0.023

Non-perforated

2.800 ± 0.297

2.829 ± 0.250

Synapse morphology (μm)

  

PSD length

0.300 ± 0.007

0.327 ± 0.006

Head Diameter

0.529 ± 0.014

0.551 ± 0.006