Tau deletion attenuates Aβ1-42-induced cell death. Cupric silver staining of 20 μm thick coronal sections in WT mice injected with lentiviral A) Aβ1-42 + DMSO, B) Aβ1-42 + Nilo, C) Aβ1-42 + Tau + DMSO, D) Aβ1-42 + Tau + Nilo and E) LacZ + DMSO. Silver staining in Tau−/− mice injected with lentiviral F) Aβ1-42 + DMSO, G) Aβ1-42 + Nilo, H) Aβ1-42 + Tau + DMSO, I) Aβ1-42 + Tau + Nilo and J) LacZ + DMSO. Histograms represent K) stereological quantification of silver-positive cells and L) caspase-3 activity. Asterisk is significantly different to Aβ1-42 + DMSO or as indicated, bars are mean ± SEM, two-way ANOVA.