| | Standardized Beta | T | p-Value |
---|
Model - Step 1 | IS | - 0.50 | - 4.0 | < 0.0001 |
Model - Step 2 | IS | 0.50 | - 4.3 | < 0.0001 |
| CAG expanded | 0.30 | 2.5 | 0.016 |
Model - Step 3 | IS | 1.1 | - 3.9 | < 0.0001 |
| CAG expanded | 0.30 | 2.6 | 0.014 |
| Shoulson | 0.60 | - 2.2 | 0.03 |
- A linear regression was performed to predict anti-AT1R antibody titers via infection, smoking and HD-relevant variables with additional variables “onset motor” and “onset psychiatric” (n = 48, i.e. only smokers with infection and motor as well as psychiatric onset of disease were included). A stepwise analysis revealed in a first step independence scale (IS), in a second step CAG expanded and in a third step the variable Shoulson scale as predictor. Other variables were not relevant for predicting the presence of anti-AT1R antibody titers in this subgroup.